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Proflora 4R | Spore-based Probiotic & Herbal Formula | Restore - 30 Capsules Oral Supplements Biocidin Botanicals
Proflora 4R | Spore-based Probiotic & Herbal Formula | Restore - 30 Capsules Oral Supplements Biocidin Botanicals
Proflora 4R | Spore-based Probiotic & Herbal Formula | Restore - 30 Capsules Oral Supplements Biocidin Botanicals
Proflora 4R | Spore-based Probiotic & Herbal Formula | Restore - 30 Capsules Oral Supplements Biocidin Botanicals

Proflora 4R | Spore-based Probiotic & Herbal Formula | Restore - 30 Capsules

Biocidin Botanicals
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Updated Formula: 33% More Spores!

Proflora 4R – a potent solution for comprehensive restoration in your gut – just got better! Biocidin has collaborated with industry leaders in microbiome science to upgrade Proflora 4R with the most well-researched, spore-forming strains available. 

The formulation still contains the same Bacillus probiotics but with new strains curated to take efficacy and outcome to the next level. They've increased potency by 33% to 4 billion CFUs, which means the company achieve evidence-based strength in a single capsule – at the same price. 

This results in even greater health benefits. A probiotic that helps keep the gut in balance so it can do its best work – support digestion, absorb nutrients, maintain regularity, and participate in facilitating healthy, balanced immune function.

The new strains of soil-based, spore-forming probiotic bacteria in Proflora 4R have been the subject of multiple double-blind, placebo-controlled studies. Shown to survive passage through the stomach into the small and large intestines – germinating within hours after consumption – it’s the perfect support in the perfect place, perfectly timed.

What hasn’t changed? Our reliance on the benefits that plants offer. Proflora 4R still contains Marshmallow Root, Aloe Vera, and Quercetin – to soothe and calm irritation in the gut lining.*

This updated formulation delivers all the benefits of Proflora 4R you’ve come to rely on – and more!

Simple is sometimes better. Proflora4R combines three probiotic microorganisms with three botanicals to give you one potent solution for comprehensive restoration in your gut.*

In just one capsule a day, Proflora4R supports optimal health in multiple ways.* Soothing the lining of the gut, addressing histamine, supporting motility.*

Proflora 4R contains three different Bacillus bacteria, all of which are human-derived and spore-forming. Together, they offer something remarkable. Shelf stability. Immunomodulation.* Survival through the GI tract. And the ability to support keystone species and restore microbial diversity, even in the presence of antibiotics.* 

The three botanicals – marshmallow root, aloe vera, and quercetin – soothe and calm.*

Proflora4R. It’s a great stand-alone choice for every day and a perfect addition to Biocidin® protocols.

Proflora™ 4R Benefits

  • Supports digestion and digestive comfort*
  • Helps manage occasional bloating, gas, and indigestion*
  • Promotes nutrient absorption*
  • Promotes regularity and normal bowel movements*
  • Maintains a healthy gut barrier*
  • Supports microbial diversity and balance in the GI tract*
  • Promotes a healthy inflammatory response and immune health*
  • Supports cardiovascular health*
  • Child-friendly support for microbial diversity and gastrointestinal health*
  • Competitive exclusion of unfavorable microbes*

Proflora™ 4R Features

  • Three clinically researched Bacillus species
  • Evidence-based levels of spore-forming probiotics
  • Organic botanical ingredients
  • Temperature stable (does not require refrigeration)
  • Survives stomach and bile acids to proliferate in the intestines (small and large within 4 hours)
  • May be taken with antimicrobials and/or antibiotics
  • Concurrent use with Biocidin® recommended
  • SIBO safe


Bring balance and healing. Undesirable microbes create imbalances, even disorder. The effort to restore harmony requires ongoing renewal – and that’s where our botanicals and nutrients shine. Offering needed provisions, they allow the body to establish balance. Plants unite with the body to revive and strengthen – cultivating microbial diversity, healthy digestion, nutrient absorption, and sustained well-being.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.



Serving Size: 1 Capsule

Servings per Container: 30

Proprietary Probiotic Blend: 4 Billion Spore Cells: LactoSpore® (Bacillus coagulans - MTCC 5856) MuniSpore (Bacillus clausii - CSI08) Bacillus subtilis DE111®
Proprietary Herbal Blend: Quercetin, Marshmallow root‡ , Aloe Vera‡ leaf gel

Other Ingredients: microcrystalline cellulose, vegetable capsule

 Organic Ingredient 



Take one capsule per day with meals or as directed by your healthcare professional.

Warning: Not recommended for use during pregnancy. Consult your physician before using any supplement, especially if you are nursing, have a medical condition, or are taking medication. Discontinue use should adverse reactions occur. Keep out of reach of children.

Store in a cool, dry place.

Customer Reviews

Based on 1 review
Allison S.
Great Product

Helps with my gut issues